The governing board of Midlands Technical College is the Midlands Technical College Commission. These 12 leading citizens are appointed by the governor, upon the recommendation of their respective legislative delegations, to serve as trustees for the college.
| Members | Business |
| Mr. Ronald H. Burkett Chair |
Burkett, Burkett & Burkett, CPAs |
| Ms. Harriet Gardin Fields Vice Chair |
H.G. Fields and Associates |
| Mr. James Smith Secretary |
Thomas & Associate Realtors |
| Mr. Christopher M. Joye Treasurer |
Joye Technology Group, LLC |
| Ms. Katie M. Bolden | Retired |
| Mr. Robert F. Dozier, Jr. | Homeowners Mortgage Enterprises |
| Mr. Robert C. Lentz | The Lentz Group |
| Ms. Judith Litman Lindau | Retired |
| Mr. David S. Murray, Jr. | Murray's Neighborhood Grill & Bar |
| Dr. Peter E. Sercer | Retired |
| Mr. Robert P. Wilkins, Jr. | RPW Development, Inc. |